People who received the Johnson & Johnson COVID-19 vaccine as their first shot showed a strong immune response when boosted with the Pfizer / BioNTech SE or Modana vaccines.
This preliminary, non-peer-reviewed study is the latest challenge to J & J’s efforts to use the COVID-19 vaccine as a booster in the United States.
The study of more than 450 adults who received their first shots from Pfizer, Modana, or Johnson & Johnson showed that different types of “mixing and matching” booster shots were safe for adults. ..
Moderna and Pfizer vaccines are based on messenger RNA, while J & J vaccines use viral vector technology.
This is because the US Food and Drug Administration advisory group is preparing to meet later this week to discuss the benefits of booster shots for Moderna and J & J vaccines.
FDA officials on Wednesday said J & J’s submission to regulators on the planned booster generated a warning signal containing a small sample size and data based on unverified tests.
After the White House announced plans to roll out boosters to most adults from last month in August, U.S. health officials are under pressure to provide advice on booster doses for the J & J and Moderna COVID-19 vaccines. ..
The NIH study compared the safety and immune response of volunteers boosted with the same type of shots given at the first vaccination with volunteers who received different types of shots as boosters.
The study said that mixing and matching booster doses produced side effects similar to those seen with primary doses and did not raise significant safety concerns.
Studies of three COVID-19 vaccines currently approved in the United States generally show that using different types of shots as boosters results in an antibody response equal to or better than using the same type. it was done.
The trial took place in 10 cities in the United States and used a total of nine combinations of first shots and boosters.
Mixing booster doses “may provide immunological benefits to optimize the range of protection and longevity achieved with currently available vaccines,” the researchers write in a study.
J & J COVID-19 Shots Get Better Boost From Moderna or Pfizer in NIH Survey-SABC News
Source link J & J COVID-19 Shots Get Better Boost From Moderna or Pfizer in NIH Survey-SABC News