But the new study also shows the inadequacies of transmitting such embryos. Most of the 144 embryos transmitted by the group had only one or two chromosomal abnormalities, but the transmission resulted in 11 abortions in addition to eight live births.
Laura Hercher, head of student research at Sarah Lawrence’s genetic counseling program, says: “There are a lot of exits and rats.
PGT-A is used to diagnose aneuploidy, which is when abnormal numbers of chromosomes are detected – or a few or more – in the target cells. A rare number of chromosomes can, in severe cases, lead to genetic defects, such as Down syndrome. Often, abnormal number of chromosomes can lead to a miscarriage, either by preventing embryos from implanting or by causing miscarriage.
But the problem with PGT-A, the authors argue, is that it provides an incomplete picture that is often described as a very definitive result. This experiment is based on looking at a few cells from the outside of a growing embryo and testing to see if each one has 23 chromosomes.
“PGT means choosing embryos that will allow a person to have a better pregnancy,” said Dr. David Barad, OB-GYN at the Center for Human Reproduction and co-author of the study said. “But genetic testing does not improve embryos, it gives us some idea of who they are.”
Although continuing to use these unhealthy embryos can be dangerous the authors of the new book, all associated with the hospital delivery, argue that Potential embryos are now overlooked, leaving many women to believe they have no other choice but to become pregnant.
“Abortion rates are what one would expect in such an old age,” Drs. Norbert Gleicher, clinical director and author of the study, said via email. He adds: “Ask women what they like. The risk of miscarriage or never having a baby. The answer is obvious. ”
Studies raise questions about genetic testing for embryos ‘non-existent’
Source link Studies raise questions about genetic testing for embryos ‘non-existent’